1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	K	S	S	F	K	I	S	N	P	L	E	A	R	M	S	E	S	S	R	I	R	E	K	Y	P	D	R	I	P	V	I	V	E	K	A	G	Q	S	D	V	P	D	I	D	K	K	K	Y	L	V	P	A	D	L	T	V	G	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?		?																													?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	V	Y	V	V	R	K	R	I	K	L	G	A	E	K	A	I	F	V	F	V	K	N	T	L	P	P	T	A	A	L	M	S	A	I	Y	E	E	H	K	D	E	D	G	F	L	Y	M	T	Y	S	G	E	N	T	F	G	S	L	T
Secondary structure
SS confidence
Disorder																									?	?	?	?	?	?										?	?	?															?	?	?	?	?
Disorder confidence
		.	.
Sequence		V	A
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 25%) Alpha helix ( 33%) Beta strand ( 23%)

Rank Aligned region

PDB 3d32 chain A domain 1 Region: 3 - 117 Aligned: 115 Modelled: 115 Confidence: 100.0% Identity: 57% Fold: beta-Grasp (ubiquitin-like) Superfamily: Ubiquitin-like Family: GABARAP-like Phyre2 PDB 3h9d chain B Region: 3 - 117 Aligned: 115 Modelled: 115 Confidence: 100.0% Identity: 54% PDB header:structural protein Chain: B: PDB Molecule:microtubule-associated protein 1a/1b, light chain 3, PDBTitle: crystal structure of trypanosoma brucei atg8 Phyre2 PDB 1eo6 chain A Region: 3 - 117 Aligned: 115 Modelled: 115 Confidence: 100.0% Identity: 60% Fold: beta-Grasp (ubiquitin-like) Superfamily: Ubiquitin-like Family: GABARAP-like Phyre2 PDB 6aag chain F Region: 1 - 115 Aligned: 115 Modelled: 115 Confidence: 100.0% Identity: 72% PDB header:membrane protein Chain: F: PDB Molecule:transmembrane protein 184 homolog ykr051w,autophagy-related PDBTitle: crystal structure of budding yeast atg8 complexed with the helical aim2 of hfl1. Phyre2 PDB 5azh chain A Region: 2 - 117 Aligned: 116 Modelled: 116 Confidence: 100.0% Identity: 34% PDB header:protein binding Chain: A: PDB Molecule:eeeweel peptide,protein lgg-2; PDBTitle: crystal structure of lgg-2 fused with an eeeweel peptide Phyre2 PDB 3vvw chain B Region: 6 - 117 Aligned: 112 Modelled: 112 Confidence: 100.0% Identity: 45% PDB header:protein transport Chain: B: PDB Molecule:microtubule-associated proteins 1a/1b light chain 3c; PDBTitle: ndp52 in complex with lc3c Phyre2 PDB 2zjd chain A domain 1 Region: 2 - 117 Aligned: 116 Modelled: 116 Confidence: 100.0% Identity: 37% Fold: beta-Grasp (ubiquitin-like) Superfamily: Ubiquitin-like Family: GABARAP-like Phyre2 PDB 2zpn chain B Region: 5 - 113 Aligned: 109 Modelled: 109 Confidence: 100.0% Identity: 72% PDB header:protein transport Chain: B: PDB Molecule:autophagy-related protein 8; PDBTitle: the crystal structure of saccharomyces cerevisiae atg8-2 atg19(412-415) complex Phyre2 PDB 3w1y chain A Region: 4 - 115 Aligned: 112 Modelled: 112 Confidence: 100.0% Identity: 36% PDB header:transport protein/ribosomal protein Chain: A: PDB Molecule:microtubule-associated protein 1a/1b, light chain 3; PDBTitle: crystal structure of t brucei atg8.2 in complex with e coli s10 Phyre2 PDB 4eoy chain B Region: 5 - 116 Aligned: 112 Modelled: 112 Confidence: 100.0% Identity: 47% PDB header:transport protein Chain: B: PDB Molecule:microtubule-associated protein 1 light chain 3; PDBTitle: plasmodium falciparum atg8 in complex with plasmodium falciparum atg32 peptide Phyre2 PDB 1klv chain A Region: 20 - 117 Aligned: 98 Modelled: 98 Confidence: 100.0% Identity: 60% Fold: beta-Grasp (ubiquitin-like) Superfamily: Ubiquitin-like Family: GABARAP-like Phyre2 PDB 4gdk chain A Region: 32 - 117 Aligned: 85 Modelled: 86 Confidence: 100.0% Identity: 24% PDB header:protein binding Chain: A: PDB Molecule:ubiquitin-like protein atg12; PDBTitle: crystal structure of human atg12~atg5 conjugate in complex with an n-2 terminal fragment of atg16l1 Phyre2 PDB 1wz3 chain A domain 1 Region: 32 - 116 Aligned: 81 Modelled: 85 Confidence: 99.9% Identity: 17% Fold: beta-Grasp (ubiquitin-like) Superfamily: Ubiquitin-like Family: APG12-like Phyre2 PDB 3w1s chain C Region: 28 - 117 Aligned: 74 Modelled: 90 Confidence: 99.8% Identity: 16% PDB header:ligase Chain: C: PDB Molecule:ubiquitin-like protein atg12; PDBTitle: crystal structure of saccharomyces cerevisiae atg12-atg5 conjugate2 bound to the n-terminal domain of atg16 Phyre2 PDB 2dym chain E Region: 8 - 109 Aligned: 90 Modelled: 102 Confidence: 96.7% Identity: 20% PDB header:protein turnover/protein turnover Chain: E: PDB Molecule:autophagy protein 5; PDBTitle: the crystal structure of saccharomyces cerevisiae atg5-2 atg16(1-46) complex Phyre2 PDB 3vqi chain E Region: 8 - 109 Aligned: 93 Modelled: 102 Confidence: 96.6% Identity: 19% PDB header:protein transport Chain: E: PDB Molecule:atg5; PDBTitle: crystal structure of kluyveromyces marxianus atg5 Phyre2 PDB 4hpm chain B Region: 42 - 111 Aligned: 69 Modelled: 69 Confidence: 96.3% Identity: 17% PDB header:transcription Chain: B: PDB Molecule:polycomb group ring finger protein 1; PDBTitle: pcgf1 ub fold (rawul)/bcorl1 pufd complex Phyre2 PDB 2na1 chain A Region: 28 - 115 Aligned: 88 Modelled: 88 Confidence: 96.2% Identity: 19% PDB header:transcription Chain: A: PDB Molecule:polycomb complex protein bmi-1, polyhomeotic-like 2; PDBTitle: uld complex Phyre2 PDB 4gdk chain B Region: 8 - 109 Aligned: 100 Modelled: 102 Confidence: 96.1% Identity: 16% PDB header:protein binding Chain: B: PDB Molecule:autophagy protein 5; PDBTitle: crystal structure of human atg12~atg5 conjugate in complex with an n-2 terminal fragment of atg16l1 Phyre2 PDB 3goe chain A Region: 43 - 95 Aligned: 53 Modelled: 53 Confidence: 85.9% Identity: 11% PDB header:recombination, replication Chain: A: PDB Molecule:dna repair protein rad60; PDBTitle: molecular mimicry of sumo promotes dna repair Phyre2 1 d3d32a1 2 c3h9dB_ 3 d1eo6a_ 4 c6aagF_ 5 c5azhA_ 6 c3vvwB_ 7 d2zjda1 8 c2zpnB_ 9 c3w1yA_ 10 c4eoyB_ 11 d1klva_ 12 c4gdkA_ 13 d1wz3a1 14 c3w1sC_ 15 c2dymE_ 16 c3vqiE_ 17 c4hpmB_ 18 c2na1A_ 19 c4gdkB_ 20 c3goeA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121